- Canine karyotype
- Molecular Cytogenetics
- Array-CGH analysis of canine tumors
- Dogs of Chernobyl – A Genetic Analysis
- Genomics of Military Working dogs
- Cancer Cytogenetics
- Canine bladder cancer – development of a new non-invasive method for early detection
- CLINICAL STUDY – Early Detection and treatment of Canine Urothelial Carcinoma
Comparative and Wildlife Genomics
- Comparative Genomics
- Wildlife Genetics and Cancer
- Galapagos Wildlife – Genetic Analysis and Health
- Population analysis of North Carolina Black Bears
Dr. Matthew Breen’s research focuses on genetics, genomics, and the comparative aspects of animal and human health. The lab uses a range of genetic and genomic technologies for evaluating changes to genome structure that occur in canine cancers. With these data we aim to improve outcomes for canine cancer patients and also advance our undestanding of the comparable cancers in people. In addition, we are assessing the impact of daily environmental exposures on animal health, as a sentinel for human health.
Dr. Breen is a Professor of Genomics and the Oscar J. Fletcher Distinguished Professor of Comparative Oncology Genetics in the Dept. of Molecular Biomedical Sciences at the NCSU College of Veterinary Medicine. He is also a member of the NCSU Comparative Medicine Institute (CMI), Center for Human Health and the Environment, and the Genetics and Genomics Initiative, as well as the Duke Cancer Institute, and the Cancer Genetics Program at the University of North Carolina’s Lineberger Comprehensive Cancer Center. Dr. Breen is a member of the NCSU Research Leadership Academy.
Dr. Breen was a charter member, and serves on the Board of Directors, of the Canine Comparative Oncology and Genomics Consortium (CCOGC), a 501c3 not-for-profit organization established to promote the role of the dog in comparative biomedical research, and also serves on the board of directors of the Canines-N-Kids Foundation, a 501c3 committed to finding a cure to the devastating cancers that canines and children face in common. He is member of the steering committee of the NCI’s Integrated Canine Data Commons and serves on the Data Governance Advisory Board of that initiative. Dr. Breen was appointed to the National Academies expert committee tasked with planning a public workshop to examine the role of companion animals as sentinels of shared environmental exposures that may impact human aging and cancer. Dr. Breen is also a charter member of the Sea Lion Cancer Consortium (SLiCC)
Dr. Breen has served on scientific review committees for organizations including the National Institutes of Health, AKC Canine Health Foundation, and the Morris Animal Foundation. He is a regular reviewer for numerous scientific funding agencies and journals . Dr. Breen serves on the editorial board of several journals and is an Associate Editor of Chromosome Research.
Support Our Research
If you are interested in making a tax deductible donation to support this research please consider visiting the North Carolina Veterinary Medical Foundation.
(Please pick a gift amount and under “Search All Funds” type “Cancer Genomics Fund”, and then add to cart)
Cancer Study Participation
If you are interested in participating our Cancer Study, please click below to learn more.