- Canine karyotype
- Molecular Cytogenetics
- Array-CGH analysis of canine tumors
- Canine bladder cancer - development of a new non-invasive method for early detection
- Gene Expression Analysis
- Canine Brain Tumor Research
- Integrated Genome Mapping
- Comparative and Wildlife Genomics
- Wildlife Forensics
Dr. Matthew Breen’s research focuses on genomics, genome mapping and the comparative aspects of canine cancer. In addition his lab is using high throughput molecular cytogenetics for anchoring emerging genome assemblies and for evaluating the changes to genome structure that occur during speciation. The lab is also developing new molecular assays for diagnostic and prognostic use in veterinary medicine.
Dr. Breen is a Professor of Genomics and the Oscar J. Fletcher Distinguished Professor of Comparative Oncology Genetics in the Dept. of Molecular Biomedical Sciences at the NCSU College of Veterinary Medicine. He is also a member of the NCSU Comparative Medicine Institute (CMI) the NCSU Genetics Program in the College of Science, and the Cancer Genetics Program at the University of North Carolina's Lineberger Comprehensive Cancer Center. Dr. Breen was a charter member, and serves on the Board of Directors, of the Canine Comparative Oncology and Genomics Consortium (CCOGC), a 501c3 not-for-profit organization established to promote the role of the dog in comparative biomedical research, and also serves on the board of directors of the Canines-N-Kids Foundation, a 501c3 committed to finding a cure to the devastating cancers that canines and children face in common. He is also a charter member of the Sea Lion Cancer Consortium (SLiCC) and a founder of Sentinel Biomedical.
Dr. Breen has served on scientific review committees for organizations including the National Institutes of Health, AKC Canine Health Foundation and the Morris Animal Foundation and is a regular reviewer for numerous scientific journals. In 2007 Dr. Breen was awarded the Asa Mays Award for Excellence in Canine Health Research. In 2013 he was the recipient of an award from the NCSU Chancellor’s Innovation Fund to develop a new genetic test that will predict how long a dog diagnosed with lymphoma and treated with chemotherapy will maintain a good quality of life. Dr. Breen serves on the editorial board of several journals and is an Associate Editor of Chromosome Research.