Matthew Breen :: PhD :: C.Biol :: FRSB ::
Professor of Genomics and the Oscar J. Fletcher Distinguished Professor of Comparative Oncology Genetics

  • Andrea Y. Angstadt, Venugopal Thayanithy, Subbaya Subramanian, Jaime F. Modiano, and Matthew Breen (2012). A genome-wide approach to comparative oncology: High-resolution oligonucleotide aCGH of canine and human OS pinpoints shared microaberrations. Cancer Genetics 205(11): 572–587(Journal link)
  • Aric M. Frantz, Aaron L. Sarver, Daisuke Ito, Tzu Lip Phang, Anis Karimpour-Fard, Milcah C. Scott, Victor E. O. Valli, Kerstin Lindblad-Toh, Kristine E. Burgess, Brian D. Husbands, Michael S. Henson, Antonella Borgatti, William C. Kisseberth, Lawrence E. Hunter, Matthew Breen, Timothy D. O’Brien, Jaime F. Modiano. (2012). Molecular profiling reveals prognostically significant subtypes of canine lymphoma. Vet Pathology. 50(4) 693-703 (Journal link)
  • Sehwon Koh, Rachael Thomas, Shengdar Tsai, Steve R. Bischoff, Ji-hey Lim, Matthew Breen, Natasha J. Olby, and Jorge A. Piedrahita (2012). Generation of induced pluripotent stem cells (iPSC) from adult canine fibroblasts. Stem Cells and Development 22(6):951-963. PubMed link
  • Antoine Italiano, Chun-Liang Chen, Rachael Thomas, Matthew Breen, Françoise Bonnet Nicolas Sevenet Michel Longy, Robert G. Maki, Jean-Michel Coindre, Cristina R. Antonescu (2012). Alterations of P53 and PIK3CA/AKT/mTOR Pathway in Angiosarcomas: A Distinct Pattern from Other Sarcomas with Complex Genomics. Cancer 118(23):5878-5887 PubMed link
  • Josely F. Figueiredo*, Sarah Culver*, Erica Behling-Kelly, Matthew Breen, Kristen Friedrichs (2012). Acute Myeloblastic leukemia with associated BCR-ABL translocation in a dog. Veterinary Clinical Pathology 31(3), 362-368 (*joint first author) (Journal linkPubMed link
  • Tsai, P.C. and Breen, M. (2012). Array-based comparative genomic hybridization–guided identification of reference genes for normalization of real-time quantitative polymerase chain reaction assay data for lymphomas, histiocytic sarcomas, and osteosarcomas of dogs. American Journal of Veterinary Research 73(9), 1335-1343. (Journal link) PubMed link
  • Venugopal Thayanithy, Aaron L. Sarver, Reena V. Kartha, ChangWon Park, Milcah Scott, Andrea C. Young, Matthew Breen, Clifford J. Steer, Jaime F. Modiano and Subbaya Subramanian (2011). Perturbation in 14q32 miRNAs-MYC-miR-17~92 gene network contributes to osteosarcoma and is associated with survival outcome. Bone 50 (1), 171-181 PubMed link
  • Shearin AL*, Hedan B*, Cadieu E, Erich SA, Schmidt EV, Faden DL, Cullen J, Abadie J, Kwon E, Gröne A, Devauchelle P, Rimbault M, Karyadi DM, Lynch M, Galibert F, Breen M, Rutteman GR, Andre C, Parker HG and Ostrander EA. (2012). The MTAP-INK4A Locus Confers Susceptibility to Cancer in a Naturally Occurring Canine Model. Cancer Epidemiol Biomarkers. Prev 012;21:1019-1027 (* contributed equally). (Journal link) PubMed link
  • Breen, M., Thomas, R. (2012). Cytogenetics and Chromosome Maps: Chapter 11 in Genetics of the Dog, 2nd Edition. Ruvinsky and Ostrander- eds. CAB International, Oxon, U.K.
  • Antoine Italiano, Rachael Thomas, Matthew Breen, Aimee Crago, Samuel Singer, Raya Khanin, Robert G Maki, Markus Hafner, Tom Tuschl, Cristina R. Antonescu. (2012). The miR-17-92 cluster microRNAs and its target THROMBOSPONDIN-1 are differentially expressed in angiosarcomas dependent on MYC amplification. Genes, Chromosome, Cancer 51(6)-569-578. PubMed link
  • Daisuke Ito, Aric Frantz, Christina Williams, Rachael Thomas, Robert C. Burnett, Anne C. Avery, Matthew Breen, Nicola J. Mason, Timothy D. O’Brien and Jaime F. Modiano (2012). CD40 ligand is necessary and sufficient to support primary diffuse large B-cell lymphoma cells in culture: a tool for in vitro preclinical studies with primary B-cell malignancies. Leukemia and Lymphoma 53, 1390-1398. PubMed link