Matthew Breen :: PhD :: C.Biol :: FRSB ::
Professor of Genomics and the Oscar J. Fletcher Distinguished Professor of Comparative Oncology Genetics

  • Hiroyuki Mochizuki, Susan G. Shapiro, Matthew Breen (2015). Detection of BRAF Mutation in Urine DNA as a Molecular Diagnostic for Canine Urothelial and Prostatic Carcinoma. PLoS One Dec 9th 2015.
  • Ingegerd Elvers, Jason Turner-Maier, Ross Swofford, Michele Koltookian, Jeremy Johnson, Chip Stewart, Cheng-Zhong Zhang, Steven E Schumacher, Rameen Beroukhim, Mara Rosenberg, Rachael Thomas, Evan Mauceli, Gad Getz, Federica Di Palma, Jaime F Modiano, Matthew Breen, Kerstin Lindblad-Toh,  Jessica Alföldi. (2015). Exome sequencing of lymphomas from three dog breeds reveals somatic mutation patterns reflecting genetic background. Genome Res. 25: 1634-1645
  • Shapiro, S, Knapp, D, and Breen, M. (2015). A cultured approach to canine urothelial carcinoma: molecular characterization of five cell line. Canine Genetics and Epidemiology 2:15 on-line access
  • Mochizuki, H. and Breen, M. (2015). Comparative Aspects of BRAF Mutations in Canine Cancers. Veterinary Sciences 2(3), 231-245 on-line access
  • Breen, M. (2015). Comparative Cytogenetics. In: eLS. John Wiley & Sons, Ltd: Chichester. DOI: 10.1002/9780470015902.a0005801.pub3 on-line access
  • Leonard NunneyCarlo C. MaleyMatthew BreenMichael E. HochbergJoshua D. Schiffman (2015). Introduction: Peto’s paradox and the promise of comparative oncology . Philosophical Transactions of the Royal Society B: Biological Sciences. 370 (1673)
  • Schiffman, J.D. and Breen, M. (2015). Comparative Oncology: What dogs and other species can teach us about humans with cancer. Philosophical Transactions of the Royal Society B: Biological Sciences. 370 (1673)
  • Mazcko, C. and Thomas, R. (2015). The Establishment of the Pfizer-Canine Comparative Oncology and Genomics Consortium Biospecimen Repository. Veterinary Sciences 2015, 2(3), 127-130.
  • Sarah C. Roode, Daniel Rotroff, Anne C. Avery, Steven E. Suter, Dorothee Bienzle, Joshua D. Schiffman, Alison Motsinger-Reif, and Matthew Breen. (2015). Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation. Chromosome Research 23(4):681-708.
  • Mochizuki, H, Kennedy, K, Shapiro, S.G., Breen, M. (2015). BRAF Mutations in Canine Cancers. PLoS One June 8 DOI: 10.1371/journal.pone.0129534 OPEN ACCESS
  • ϕOmeir, R., ϕ,Thomas, R., Teferedegne, B., Williams, C., Foseh, G., Macauley, J., Brinster, L., Beren, J., Peden, K., Breen, M., Lewis, A. M. Jr. (2015). A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity. Chromosome Research DOI 10.1007/s10577-015-9474-8. ϕ equal contribution. OPEN ACCESS
  • Shapiro, S.G., Raghunath, S., Williams, C., Motsinger-Reif, A., Cullen, J.M., Liu, T., Albertson, D., Ruvolo, M., Bergstrom Lucas, A., Jin, J., Knapp, D. Schiffman, J.D. and Breen, M (2015). Canine urothelial carcinoma: genomically aberrant and comparatively relevant. Chromosome Research 23:311–331
  • Noriko Tonomura, Ingeggerd Elvers, Rachael Thomas, Katherine Megquier, Elinor Karlsson, Jason Turner-Maier, Cedric Howard, Aaron Sarver,  Ross Swofford, Aric Frantz, Daisuke Ito, Evan Mauceli, Maja Arendt, Hyun Ji Noh, Michele Koltookian, Tara Biagi, Sara Fryc, Chrsitine Williams, Anne Avery, Jong-Hyuk Kim, Lisa Barber, Kristine Burgess, Eric Lander, Elinor Karlsson, Chieko Azuma, Jaime Modiano†, Matthew Breen†, Kerstin Lindblad-Toh†  (co-senior authors). Genome-wide association study identifies shared risk loci common to two malignanciesin golden retrievers. PLoS Genetics. 02/2015; 11(2):e1004922.
  • Kelsey Poorman, Luke Borst, Scott Moroff, Siddharth Roy, Philippe Labelle, Alison Motsinger-Reif, and Matthew Breen (2015). Comparative Cytogenetic Characterization of Primary Canine Melanocytic Lesions using Array CGH and Fluorescence in situ Hybridization. Chromosome Research 23:171-186.